Reye's Syndrome
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چکیده
This is a rare syndrome, characterised by an acute, life-threatening, non-inflammatory encephalopathy and fatty degeneration of the liver with minimal or no clinical signs of liver involvement. In classic Reye's syndrome, there is a severe but self-limiting disturbance of mitochondrial structure and associated enzymatic disturbances usually lasting about six days. This is accompanied by an intense, acute catabolic state associated with cerebral oedema in the absence of encephalitis or meningitis.
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Co-existence of hepatitis A and adult Reye's syndrome.
Reye's syndrome is most frequently seen in children but has also been described in adults. This syndrome is usually associated with ingestion of 5-aminosalicylates (ASA) or infection with influenza A, influenza B, or varicella virus. A case of Reye's syndrome in a 47 year old, previously healthy woman precipitated by ingestion of ASA and acute hepatitis A virus infection is described. Reye's sy...
متن کاملReye's syndrome in the United States from 1981 through 1997.
BACKGROUND Reye's syndrome is characterized by encephalopathy and fatty degeneration of the liver, usually after influenza or varicella. Beginning in 1980, warnings were issued about the use of salicylates in children with those viral infections because of the risk of Reye's syndrome. METHODS To describe the pattern of Reye's syndrome in the United States, characteristics of the patients, and...
متن کاملInfluenza A virus and Reye's syndrome in adults.
We report fatal Reye's syndrome in two adults following proven influenza A viral infections. Reye's syndrome is, therefore, not confined to children but may also occur in adults. Many reported cases of postinfluenza A encephalopathy have clinical and pathological features of Reye's syndrome suggesting that they are not due to postinfectious perivenous demyelination.
متن کاملReye's syndrome and the use of aspirin.
In 1986 there was a public warning in the United Kingdom about a link between the consumption of aspirin and Reye's syndrome. To find out if the use of aspirin and paracetamol in children had altered, and whether the incidence of Reye's syndrome had changed since a previous study, parents were interviewed in Belfast and London, and the British Reye's Syndrome Surveillance System data were revie...
متن کاملOrnithine carbamyl transferase in Reye's syndrome.
Serum levels of ornithine carbamyl transferase activities were determined in the acutely ill and convalescent Reye's syndrome patients and in their parents. Acutely ill Reye's syndrome patients had elevated levels of serum ornithine carbamyl transferase activities as compared to those in controls. The convalescent Reye's syndrome patients and their parents had normal levels of serum ornithine c...
متن کاملReye's syndrome in the British Isles: first annual report of the joint British Paediatric Association and Communicable Disease Surveillance Centre surveillance scheme.
Reye's syndrome is a severe acute paediatric disorder characterised by encephalopathy with pronounced cerebral oedema and by diffuse fatty infiltration of the viscera, particularly the liver.' It may occur at any age in childhood. Typically a previously normal child has a viral type prodromal illness followed in a few days by vomiting, altered consciousness, and often convulsions. The liver may...
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